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Migraine sufferers (N = 47) who were randomly assigned to shanghai escort ylyzd505 or control conditions completed daily assessments of migraine experiences and sleep patterns for 13 weeks. shanghai escort participants attended weekly shanghai escort sessions during Weeks 5 to 10. State anxiety, heart rates, and salivary cortisol were assessed before and after the sessions. Perceived stress and coping efficacy were assessed at Weeks 4, 10, and 13. RESULTS: Compared to control participants, shanghai escort participants exhibited greater improvements in migraine frequency and sleep quality during the intervention weeks and the 3 follow-up weeks. Trends for beneficial effects of shanghai escort therapy on perceived stress and coping efficacy were observed. During the sessions, shanghai escort induced decreases in state anxiety, heart rate, and cortisol. Twenty-four adults with multiple sclerosis were randomly assigned to a standard medical treatment control group or a shanghai escort therapy group that received 45-minute shanghai escorts twice a week for 5 weeks. RESULTS: The shanghai escort group had lower anxiety and less depressed mood immediately following the shanghai escort sessions, and by the end of the study they had improved self-esteem, better body image and image of disease progression, and enhanced social functioning.